GS-CMLS Guest Lecture: Dr. Charles Guttmann

Monday, 6 September 2010, at 16.00 in Room 68/69, Ground Floor, Building 64

Charles R. G. Guttmann is the Director of the Center for Neurological Imaging at Brigham & Women's Hospital ( and an Assistant Professor in Radiology at Harvard Medical School, USA.

"Ibis redibis non morietur in bello: imaging and predicting the course of syndromes affecting central nervous system white matter"

Syndromes such as multiple sclerosis (MS) are very heterogeneous with respect to prognosis, disease course, and response to treatment. Underlying pathogenesis is likely to involve multiple, genetically predisposing factors and their interaction with exogenous conditions, such as infectious, nutritional, toxic, and environmental elements.
This talk will analyze the role of imaging and quantitative image analysis in understanding pathogenesis and searching for clinically and pathologically predictive factors. A pathogenic model of diseases affecting CNS white matter will be illustrated with examples from MS and age-related syndromes, including mobility and cognitive decline.