Location: MIC-Arena, Maria-Goeppert-Str. 3, 23562 Lübeck
Title: Automatic segmentation, classification and alignment of consecutive sections for block centric navigation
Abstract: Pathology evaluates topological and morphological and immune-histochemical changes in histological structures based on tissue sections. One section offers only limited information but most diagnostic decisions require multiple sections, stains or even both. Not only conventional but also digital pathology proves low efficiency in block-based slide handling and colocalization of regions of interest through multiple sections of the same block.
Biopsies and surgical specimens have different configurations of tissue. In general multiple biopsy sections are mounted on one glass slide. Here they may contain several tissue particles. In contrast only one or two sections of surgical specimen are mounted to one slide containing one tissue particle only. We introduce a method for an automatic analysis of serial sections of both specimen types in a routine environment to extract required information for subsequent block centric navigation
